Platelet-Derived Growth Factor alpha Receptor

A PDGF receptor that binds specifically to both PDGF-A chains and PDGF-B chains. It contains a protein-tyrosine kinase activity that is involved in SIGNAL TRANSDUCTION.

Also Known As:

Receptor, Platelet-Derived Growth Factor alpha; CD140a Antigen; PDGFR2; PDGFRalpha; Antigen, CD140a; Platelet Derived Growth Factor alpha Receptor; Antigens, CD140a; CD140a Antigens; PDGF alpha Receptor; PDGF-R-alpha; Receptor, PDGF alpha

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein-Tyrosine Kinases: 7697
        Receptor Protein-Tyrosine Kinases: 5999
        Platelet-Derived Growth Factor Receptors: 2175
        Platelet-Derived Growth Factor alpha Receptor: 224
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Receptor Protein-Tyrosine Kinases: 5999
        Platelet-Derived Growth Factor Receptors: 2175
        Platelet-Derived Growth Factor alpha Receptor: 224
      - Peptide Receptors: 1159
        Growth Factor Receptors: 2663
        Platelet-Derived Growth Factor Receptors: 2175
        Platelet-Derived Growth Factor alpha Receptor: 224
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein-Tyrosine Kinases: 7697
      - Receptor Protein-Tyrosine Kinases: 5999
        Platelet-Derived Growth Factor Receptors: 2175
        Platelet-Derived Growth Factor alpha Receptor: 224

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Disease

Drug/Important Bio-Agent (IBA)